Synthesis of Pinacol 4-Hydroxyphenyl Boronate

  • Synblock
  • 20 Jul, 2014
Synthesis of Pinacol 4-Hydroxyphenyl Boronate

Pinacol 4-Hydroxyphenyl Boronate was synthesised in 28.2% overall yield from 4-bromophenol by protection 

with t-butyldimethylsilyl chloride,Grignard reaction and reaction with B(OCH3)3 to afford dimethyl 

t-butyldimethylsilyloxyphenyl boronate followed by ester exchange with pinacol and then deprotection.


269409-70-3